Granular cell breast tumour

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A granular cell tumor GrCT of the breast is an uncommon, usually benign tumor which is possibly of neural origin. The age range of presentation, however, can be very variable although they occur more commonly in pre-menopausal women. Clinically they can mimic carcinoma because of their fibrous consistency and their hardness, thus presenting as a palpable mass.

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A year-old multiparous woman with no particular past personal family history was referred after a right breast lesion ACR class 5 was found on ultrasound in a routine breast assessment. She had no palpable abnormalities and her axillary fossae were clear. Subtle architectural distortion of the supero-external quadrant of the right breast, which is difficult to detect on postero-anterior a and lateral-internal b views, because of the BI-RADS classification type III breast density.

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Colleague's E-mail is Invalid. Your message has been successfully sent to your colleague. Save my selection. There are no effective preventive measures for GCTs, early detection combined with a thorough and wide complete resection of the tumor remains the best treatment for a favorable outcome.

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It usually appears in the tongue and sometimes may affect the female breast. Initially, GCT was considered to be a myogenic lesion affecting female breast myoblastoma. Actually, it is assumed as a tumor originating from perineural or putative Schwann cells of peripheral nerves or their precursors that grows in the lobular breast tissue, due to the immunohistochemical features.

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A granular cell tumorsometimes also called breast granular cell myoblastomais an uncommon neoplastic cell growth than originates in the Schwann cells of the peripheral nervous system. Breast granular cell tumors are usually benignbut there are some rare examples of malignant presentation. I just want to let you know that I have created a newer version of this page with more up-to-date information on Granular Cell Breast Tumors.

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A granular cell tumor involving the breast parenchyma was first described by Abrikossoff in We present this case because of the rarity of this tumor. It is frequently confused with breast carcinoma on clinical and radiological examination, and its diagnosis can therefore be challenging for clinicians, radiologists and pathologists.

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Rah Medical Centre, Karachi. Sheema H. Granular cell tumors granular cell rnyoblastoma are neoplasms Which pursue a benign clinical course in large majority of cases. Tongue is the classic location for this tumor, however, rarely it is seen ill many other sites.

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Granular cell tumor is a soft tissue neoplasm that originates in the nervous system and arises at virtually any body site, but is mainly found in the skin, oral cavity or digestive tract. We report on our findings in six patients who developed granular cell tumor in the mammary gland, esophagus, subcutaneous tissue and muscle. Of six patients, two had granular cell tumor located in the breast, two in the submucosa of the esophagus, and the other two under the skin of the left axillary cavity and in the right latissimus dorsi muscle, respectively.

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